Diethyl Succinate

AKA: 123-25-1, Diethyl butanedioate, Butanedioic acid, Diethyl ester, Succinic acid diethyl ester, 1, 4-diethyl butanedioate, 4-diethyl ester, Succinic acid, FEMA No. 2377
Synthetic
Emollient
Solvent
Skin Conditioner
Clean
OriginSynthesized from succinic acid and ethanol, both petroleum-derived or bio-based organic compounds. Produced through esterification reaction of succinic acid with ethanol using acid catalysts.
Diethyl succinate has been reported in Opuntia ficus-indica, Couroupita guianensis, and other organisms with data available.
Solubility 19.1 mg/mL at 25 °C
Formula
C8H14O4
Mol. Weight
174.19
CAS #
123-25-1
Form
Liquid
State
Colorless liquid; [ICSC]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Plasticiser
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2012
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR