Diethylene Glycol Diethylhexanoate/Diisononanoate

AKA: 2'-Oxydiethanol, 2-(2-Hydroxyethoxy)ethanol, 2'-Oxybisethanol, Diglycol
Synthetic
Emollient
Skin Conditioner
Hair Care
Clean
OriginSynthesized from diethylene glycol and branched-chain carboxylic acids (3,5,5-trimethylhexanoic and 2-ethylhexanoic acid). Produced through esterification reactions combining the glycol with the two different carboxylic acids.
Oxybis(2-hydroxyethyl), diesters with 3,5,5-trimethylhexanoic acid and 2-ethylhexanoic acid
Formula
C4H10O3
Mol. Weight
106.12
CAS #
111-46-6
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
0%50%100%
Reg. limit 0.1%
EU regulatory limit: 0.1%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 186.
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR