murphyDiethylhexyl Sebacate
AKA: Di-n-octyl sebacate, Dioctyl sebacate, Dioctyl decanedioate, Decanedioic acid, Dioctyl ester, Witamol 500, Sebacic acid
Synthetic
Emollient
Occlusive
Solvent
Skin Conditioner
Clean
OriginSynthesized from sebacic acid and 2-ethylhexanol, both petroleum-derived organic compounds. Produced through esterification, where sebacic acid reacts with 2-ethylhexanol under acid catalysis to form the ester.
Bis(2-ethylhexyl) sebacate
Formula
C26H50O4
Mol. Weight
426.70
CAS #
122-62-3
Form
Powder
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Plasticiser
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 528)
Not a Skin Irritant
3 studies / 3 not irritating (CIR 528)
Not a Sensitizer
2 studies / 2 not sensitizing / plus 1 case report (CIR 528)
Concentration Guide
Leave-on0.5–5%
Rinse-off1%
0%50%100%
CIR reported use · 2010 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR