Diglycerin
molecular structure · PubChem
AKA: Diglycerol, 3-(2, 3-dihydroxypropoxy)propane-1, 2-diol, 59113-36-9, 3-glyceryloxypropane-1, Glycerol dimer, RESASSOL DN, DIGLYCERIN 801, GREAT OIL DI 1
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Synthetic
Skin Conditioner
Synthetic
Clean
OriginTypically derived from coconut, palm kernel, or soybean oils as starting materials. Produced through glycerol esterification or polymerization of plant-derived glycerin molecules.
Diglycerol has been reported in Triticum aestivum and Stelletta with data available.
Formula
C6H14O5
Mol. Weight
166.17
CAS #
59113-36-9, 25618-55-7
Form
Liquid
State
Other Solid; Liquid
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Draws water to skin
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Mixed Skin Irritation Results
5 studies / 1 irritating / 4 not irritating (CIR 884)
Mixed Sensitization Results
6 studies / 1 sensitizing / 5 not sensitizing (CIR 884)
Mixed Eye Irritation Results
6 studies / 5 irritating / 1 not irritating / reactions minimal to moderate (CIR 884)
Concentration Guide
Leave-on0.2–8%
Rinse-off0.5–28%
0%50%100%
CIR reported use · report published 2023
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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