Dihexyl Adipate

AKA: Dihexyl hexanedioate, 110-33-8, Hexanedioic acid, Dihexyl ester, Di-n-hexyl adipate, Adipic acid, Plasticizer dihexyl adipate
Synthetic
Emollient
Solvent
Skin Conditioner
Not Clean
Di-n-hexyl adipate is a colorless liquid. Floats on water. (USCG, 1999)
Formula
C18H34O4
Mol. Weight
314.50
CAS #
110-33-8
Form
Liquid
State
Di-n-hexyl adipate is a colorless liquid. Floats on water. (USCG, 1999)
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Synthetic ester developed in cosmetic chemistry as a non-greasy emollient. Created to mimic the skin-conditioning properties of plant oils while offering better oxidative stability.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR