Diisocetyl Adipate

AKA: 59686-69-0, Hexanedioic acid, Diisohexadecyl ester, AEC DIISOCETYL ADIPATE, HEXANEDIOIC ACID, 1'-DIISOHEXADECYL ESTER, DIISOCETYL ADIPATE [INCI]
Synthetic
Emollient
Solvent
Skin Conditioner
Not Clean
OriginDerived from adipic acid and isocetyl alcohol, both petroleum-based synthetic compounds. Synthesized through esterification, combining adipic acid with isocetyl alcohol via catalytic reaction.
Bis(2-hexyldecyl) adipate
Formula
C38H74O4
Mol. Weight
595.00
CAS #
57533-90-1, 58262-41-2, 59686-69-0
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 528)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2012
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR