murphyDiisocetyl Dodecanedioate
AKA: 131252-83-0, Dodecanedioic acid, Diisohexadecyl ester, 1, 12-diisohexadecyl ester, DIISOCETYL DODECANEDIOATE [INCI], Bis(14-methylpentadecyl) dodecanedioate
Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Not Clean
OriginDerived from long-chain alcohols and dodecanedioic acid, both synthetically produced chemical compounds. Synthesized through esterification reaction between the alcohol and carboxylic acid components.
Dodecanedioic acid, diisohexadecyl ester
Formula
C44H86O4
Mol. Weight
679.10
CAS #
131252-83-0
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 528)
Not a Skin Irritant
2 studies / 2 not irritating (CIR 528)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 528)
Concentration Guide
Leave-on0.9–7%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2012
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR