Diisooctyl Sebacate

AKA: Dioctan-2-yl decanedioate, 10340-41-7, Di(octan-2-yl) decanedioate, GCODXQZNEMRCBU-UHFFFAOYSA-N, Sebacic acid, Di(2-octyl) ester, Decanedioic acid bis-(1-methyl-heptyl) ester
Synthetic
Antioxidant
Emollient
Skin Conditioner
Not Clean
OriginDerived from sebacic acid (a dicarboxylic acid) and isooctyl alcohol through esterification chemistry. Synthesized by esterification reaction between sebacic acid and isooctyl alcohol under catalytic conditions.
Diisooctyl Sebacate is a cosmetic ingredient used as antioxidant, plasticiser, skin conditioning. Also known as Dioctan-2-yl decanedioate. Assessed as safe by the CIR.
Formula
C26H50O4
Mol. Weight
426.70
CAS #
10340-41-7
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on1–3%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2012
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR