diisopropyl adipate

AKA: Diisopropyl Adipate (DIPA)
Plant-Derived Synthetic
Emollient
Solvent
Skin Conditioner
Clean
OriginDerived from adipic acid and isopropyl alcohol, both petroleum-derived or synthesized from plant-based feedstocks. Synthesized through esterification of adipic acid with isopropanol via acid-catalyzed condensation.
Diisopropyl adipate
CAS #
6938-94-9
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Plasticiser
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
6 studies / 6 not sensitizing (CIR 206 and 528)
Not Phototoxic
Human test and Product formulation test found no phototoxicity in the CIR safety assessment (CIR 206 and 528)
Mixed Eye Irritation Results
7 studies / 3 irritating / 1 mixed / 3 not irritating / reactions minimal (CIR 206 and 528)
Mixed Skin Irritation Results
19 studies / 8 irritating / 3 mixed / 8 not irritating / reactions minimal to moderate (CIR 206 and 528)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2012
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR
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