murphyDiisopropylamine
AKA: 108-18-9, N-Diisopropylamine, N-(1-Methylethyl)-2-propanamine, 2-Propanamine
Synthetic
Not Clean
On the basis of the data presented in this report, the CIR Expert Panel concludes that Diisopropylamine is safe as a cosmetic ingredient as presently used. Diisopropylamine should not be used in products containing N-nitrosating agents.
Solubility Slightly soluble (NTP, 1992)
Formula
C6H15N
Mol. Weight
101.19
CAS #
108-18-9
Form
Liquid
State
Diisopropylamine appears as a clear colorless liquid with an ammonia-like odor. Flash point 30 °F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Buffering
Stabilizes pH
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 69)
Eye Irritant in Testing
2 studies / 2 irritating / reactions severe to corrosive (CIR 69)
Mixed Skin Irritation Results
3 studies / 2 irritating / 1 mixed / reactions moderate to corrosive (CIR 69)
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR