AKA: Diisostearyl maleate, 112385-09-8, Diisooctadecyl ester, 1, 4-diisooctadecyl ester, Bis(16-methylheptadecyl) (Z)-but-2-enedioate
Plant-Derived
Emollient
Skin Conditioner
Clean
2-Butenedioic acid (2E), bis(16-methylheptadecyl) ester
CAS #
112385-09-8, 113431-53-1, 680206-25-1
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
The paper trail
🔬Peer-reviewednone on file
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 464)
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 464)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 464)
Regulatory Status
JAPAN⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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