Dimethicone/Silsesquioxane Copolymer
molecular structure · PubChem
AKA: Silicone Copolymer, Silicone Resin
Synthetic
Occlusive
Skin Conditioner
Hair Care
Silicone
Clean
Dimethicone/Silsesquioxane Copolymer is a siloxane polymer consisting of methyl trimethoxysilane and dimethylsiloxane
CAS #
68440-84-6
Form
Liquid
State
Solid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Hair Fixing
Creates Protective Barrier
Conditions Hair
Creates protective layer
Softens and detangles hair
Holds hair in place
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
Restricted By
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2016 survey
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR
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