Dimethyl Succinate
molecular structure · PubChem
AKA: 106-65-0, Dimethyl butanedioate, Dimethylsuccinate, Butanedioic acid, Dimethyl ester, Succinic acid, Methyl butanedioate, FEMA No. 2396, 1, 4-dimethyl butanedioate
Synthetic
Emollient
Solvent
Skin Conditioner
Clean
Dimethyl succinate has been reported in Astragalus mongholicus and Astragalus membranaceus with data available.
Solubility greater than or equal to 100 mg/mL at 73 °F (NTP, 1992)
Formula
C6H10O4
Mol. Weight
146.14
CAS #
106-65-0
Form
Liquid
State
Dimethyl succinate is a colorless liquid. (USCG, 1999)
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Developed in the 20th century as a synthetic compound. Used in cosmetics as a humectant and conditioning agent; has no traditional medicinal history.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR