Dioctyl Adipate

AKA: 123-79-5, Dioctyl hexanedioate, Di-n-octyl adipate, Hexanedioic acid, Dioctyl ester, Dicaprylyl adipate, Adipic acid, 1, 6-dioctyl hexanedioate
Synthetic
Skin Conditioner
Not Clean
Dioctyl adipate has been reported in Streptomyces with data available.
Solubility INSOL IN WATER @ 25 °C; INSOL OR VERY SLIGHTLY SOL IN GLYCERINE & GLYCOLS; SOL IN MOST ORGANIC SOLVENTS
Formula
C22H42O4
Mol. Weight
370.60
CAS #
123-79-5
Form
Liquid
State
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Traditional Use
A synthetic plasticizer and emollient developed in the 20th century. Used in cosmetics to improve product texture and skin feel; has no traditional history.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory0 listings
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR