Disodium Cocoamphodipropionate

AKA: AMPHOSOL 2CSF, COLATERIC 2CM, ZOHARTERIC D-SF, MACKAM 2CSF, AMPHOTERGE K-2, JEETERIC CEM-38, PROTERIC CEM-38
Synthetic
Cleanser
Skin Conditioner
Hair Care
Clean
OriginPlant-Derived
beta-Alanine, N-(2-aminoethyl)-N-[2-(2-carboxyethoxy)ethyl]-, N-coco acyl derivs., disodium salts
Formula
C10H18N2Na2O5
Mol. Weight
292.24
CAS #
68411-57-4
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Hydrotrope
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 131)
Not a Sensitizer
2 studies / 2 not sensitizing / plus 2 case reports (CIR 131 and 886)
Mixed Skin Irritation Results
4 studies / 1 irritating / 1 mixed / 2 not irritating / reactions mild / plus 1 case report (CIR 131 and 886)
Concentration Guide
Leave-onNot reported
Rinse-off2–14.8%
0%50%100%
CIR reported use · 2025 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR