Disodium Etidronate

Disodium Etidronate 1
molecular structure · PubChem CID 23894
AKA: Etidronate disodium, 7414-83-7, Disodium ethydronate, Sodium ethidronate, Sodium ethydronate, Etidronic Acid Disodium Salt, Turpinal 2NZ, Disodium ethanol-1, 1-diphosphonate
Synthetic
Chelating Agent
Not Clean
OriginDerived from phosphonic acid chemistry, belonging to the diphosphonate compound family. Synthesized through phosphorylation of ethylidene diphosphonic acid, then neutralized with sodium hydroxide.
Disodium dihydrogen (1-hydroxyethylidene)bisphosphonate
Formula
C2H6Na2O7P2
Mol. Weight
249.99
CAS #
7414-83-7
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Antioxidant Protection
Binds metal ions
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 729)
Mixed Skin Irritation Results
1 study / 1 mixed / reactions slight (CIR 729)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions moderate (CIR 729)
Concentration Guide
Leave-onNot reported
Rinse-off0.04–0.097%
0%50%100%
CIR reported use · 2015 survey
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR