Disodium Glycyrrhizate
molecular structure · PubChem
AKA: 71277-79-7, Disodium glycyrrhizin, CCRIS 1966, Glycyrrhizinic acid disodium salt, DISODIUM GLYCYRRHIZATE [WHO-DD], Alpha-D-Glucopyranosiduronic acid, Disodium salt
Synthetic
Skin Conditioner
Not Clean
.alpha.-D-Glucopyranosiduronic acid (3.beta., 20.beta.)-20 -carboxy-11-oxo-30-norolean-12-en-3-yl 2-0-.beta.-D-glucopyranurosyl-, disodium salt
Formula
C42H59Na2O16-
Mol. Weight
865.90
CAS #
71277-79-7
Form
Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Brightens uneven skin tone
Evens pigmentation
Quells irritation
Traditional Use
Derived from licorice root (used for over 4,000 years in Traditional Chinese Medicine and Ayurveda); the disodium salt form was developed to provide anti-inflammatory and skin-soothing benefits in modern cosmetics.
Skin Types
●all-skin-types
Best For
Redness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR