murphyDisodium Laureth Sulfosuccinate
AKA: Disodium 4-(2-(dodecyloxy)ethyl) 2-sulphonatosuccinate, 94108-10-8, Butanedioic acid, 4-(2-(dodecyloxy)ethyl) ester, Sodium salt (1:2), 4-(2-dodecoxyethoxy)-4-oxo-2-sulfonatobutanoate Disodium
Synthetic
Cleanser
Clean
OriginDerived from coconut or palm oil-derived lauryl alcohol and maleic anhydride as primary starting materials. Synthesized through sulfonation and neutralization with sodium hydroxide to create the sulfosuccinate ester.
Poly(Oxy-1,2-Ethanediyl), .alpha.-(3-Carboxy-1-Oxo-3-Sulfopropyl)-.omega.-(Dodecyloxy)-, Disodium Salt
Formula
C18H32Na2O8S
Mol. Weight
454.50
CAS #
39354-45-5, 40754-59-4, 42016-08-0, 58450-52-5, 68815-56-5
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foaming
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Hydrotrope
Surfactant Cleansing
Surfactant Foam Boosting
Antimicrobial
Fights Acne
Anti-Inflammatory
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Comedogenic
Animal test found no comedogenicity in the CIR safety assessment (CIR 589)
Not a Sensitizer
4 studies / 4 not sensitizing (CIR 589)
Eye Irritant in Testing
3 studies / 3 irritating / reactions moderate to strong (CIR 589)
Mixed Skin Irritation Results
9 studies / 4 irritating / 1 mixed / 4 not irritating / reactions weak to severe (CIR 589)
Concentration Guide
Leave-on0.06–2%
Rinse-off0.4–10%
0%50%100%
CIR reported use · 2011 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR