Disodium Succinoyl Glycyrrhetinate

AKA: CARBENOXOLONE SODIUM, Bioral, Sanodin, Biogastrone, 7421-40-1, Neogel, Ulcus-tablinen, Sodium carbenoxolone, Berkobiogastrone, Carbenoxolone disodium salt
Synthetic
Cleanser
Skin Conditioner
Not Clean
20beta-Olean-12-en-29-oic acid, 3(beta)-(3-carboxy-1-oxopropoxy)-11-oxo-, disodium salt
Formula
C34H48Na2O7
Mol. Weight
614.70
CAS #
7421-40-1
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Locks in moisture
Traditional Use
Created as a modern specialty ingredient combining succinic acid with glycyrrhetinin (from licorice root). Designed to provide anti-inflammatory and skin-soothing benefits in contemporary skincare.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Irritation
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR