Distearyl Ether

AKA: Dioctadecyl ether, 6297-03-6, Octadecyl ether, Octadecane, COSMACOL SE
Plant-Derived
Skin Conditioner
Clean
OriginTypically derived from coconut, palm kernel, or soybean oils as starting materials. Produced through catalytic hydrogenation and etherification of fatty alcohols or fatty acid derivatives.
Dioctadecyl ether
Formula
C36H74O
Mol. Weight
523.00
CAS #
6297-03-6
Form
Wax
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
2 studies / 2 not irritating (CIR 831)
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 831)
Not an Eye Irritant
1 study / 1 not irritating (CIR 831)
Concentration Guide
Leave-on0.05%
Rinse-off0.23%
0%50%100%
CIR reported use · report published 2026
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
murphy