Dodecanedioic Acid
molecular structure · PubChem
AKA: 693-23-2, 1, 12-Dodecanedioic acid, 10-Decanedicarboxylic acid, Decamethylenedicarboxylic acid, 10-Dicarboxydecane, CHEBI:4676
Synthetic
Skin Conditioner
Acid
Not Clean
Dodecanedioic acid is an alpha,-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids. It has a role as an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor and a human metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid. It is a conjugate acid of a dodecanedioate(2-). It derives from a hydride of a dodecane.
Solubility SOL IN HOT TOLUENE, ALC, HOT ACETIC ACID; SLIGHTLY SOL IN HOT WATER
Formula
C12H22O4
Mol. Weight
230.30
CAS #
693-23-2
Form
Liquid
State
Dry Powder; Other Solid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Developed as a synthetic dicarboxylic acid for cosmetic formulation. Used in modern skincare as a buffering and pH-adjusting agent, with no significant traditional use history.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR