Dodecylhexadecyltrimonium Chloride

Dodecylhexadecyltrimonium Chloride 1
molecular structure · PubChem CID 21917627
AKA: Tetrasal, Quartamin 280GP, 103807-18-7, (2-Dodecylhexadecyl)trimethylammonium chloride, N-(2-dodecyl)hexadecyl-N, N-trimethylammonium chloride, 1-Hexadecanaminium, 2-dodecyl-N, Chloride (1:1)
Synthetic
Cleanser
Emulsifier
Skin Conditioner
Hair Care
Not Clean
OriginDerived from long-chain fatty alcohols and quaternary ammonium compounds, belonging to the cationic surfactant chemical family. Synthesized through quaternization of tertiary amines with long-chain alkyl halides via nucleophilic substitution.
1-Hexadecanaminium, 2-dodecyl-N,N,N-Trimethyl-, chloride
Formula
C31H66ClN
Mol. Weight
488.30
CAS #
103807-18-7
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Reduces Static
Conditions Hair
Cleansing Surfactant
Emulsifier
Lifts away dirt and oil
Reduces flyaways
Softens and detangles hair
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2012
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR