Ethyl Glycolate
molecular structure · PubChem
AKA: 623-50-7, Ethyl hydroxyacetate, Ethyl glycollate, Hydroxyacetic acid ethyl ester, GLYCOLIC ACID, ETHYL ESTER, Acetic acid, Ethyl ester
Synthetic
Skin Conditioner
Chemical Exfoliant
Not Clean
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Ethyl Glycolate...
Formula
C4H8O3
Mol. Weight
104.10
CAS #
107-21-1
Form
Powder
State
Clear colorless liquid; [Acros Organics MSDS]
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Shields from UV damage
Traditional Use
Developed as a synthetic hydroxy acid in the late 20th century. Became popular in skincare products during the 1980s-1990s as a gentler alternative to glycolic acid for gentle exfoliation and skin renewal.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Restricted By
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Regulatory Agencies
Skin Types
●all-skin-types
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR