Ethyl Methacrylate

AKA: 97-63-2, Ethyl 2-methylprop-2-enoate, 2-Propenoic acid, Ethyl ester, Ethyl 2-methylacrylate, Ethyl 2-methyl-2-propenoate, Rhoplex AC-33, Ethyl 2-methacrylate, METHACRYLIC ACID, ETHYL ESTER, RCRA waste number U118
Synthetic
Not Clean
OriginDerived from methacrylic acid and ethanol, both petroleum-derived organic compounds. Synthesized through esterification reaction between methacrylic acid and ethanol using acid catalysts.
Based on the available data on the formulation of nail products containing Ethyl Methacrylate, the CIR Expert Panel concludes that this ingredient is safe as used when application is accompanied by directions to avoid skin contact because of the sensitizing potential of Ethyl Methacrylate.
Solubility 5 to 10 mg/mL at 68 °F (NTP, 1992)
Formula
C6H10O2
Mol. Weight
114.14
CAS #
97-63-2
Form
Powder
State
Ethyl methacrylate appears as a colorless moderately toxic liquid with an acrid odor. Flash point of 70 °F. Boiling point 278 °F. Vapors irritate the eyes and respiratory system. Less dense than water
Skin Types
●all-skin-types
Best For
General
Functions
Viscosity Controlling
Controls Viscosity
UV Protection
Antioxidant Protection
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
—
CIR Safety Findings
Eye Irritant in Testing
2 studies / 2 irritating (CIR 19 and 321)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 not irritating / plus 2 case reports (CIR 19 and 321)
Mixed Sensitization Results
9 studies / 3 sensitizing / 3 mixed / 3 not sensitizing / plus 9 case reports (CIR 19 and 321)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR