Ethylene Glycol

Ethylene Glycol molecular structure
molecular structure · PubChem
AKA: 2-butyl-1, 4-dioxaspiro[4.4]nonane, 1, 4-Dioxaspiro[4.4]nonane, 2-Butyl-1, 4-dioxaspiro(4.4)nonane, 4-Dioxaspiro(4.4)nonane, 4-Dioxaspiro4.4nonane
Synthetic
Fragrance
Not Clean
2-Butyl-1,4-dioxaspiro(4.4)nonane; 1,2,O-2-(tert-Butyl)ethyleneglycol
Formula
C11H20O2
Mol. Weight
184.27
CAS #
78649-62-4
Form
Liquid
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Adds Fragrance
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Traditional Use
First synthesized in 1859; became widely produced industrially in the 20th century. Adopted in cosmetics as a humectant and solvent, particularly in anti-freeze and moisture-retention skincare formulations.
EWG
6
CIR
Reviewed by CIR
Pregnancy
Caution
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR