Etidronic Acid

AKA: 2809-21-4, 1-Hydroxyethylidene-1, 1-diphosphonic acid, HEDP, EHDP, Etidronsaeure, Turpinal SL, Acetodiphosphonic acid, Hydroxyethanediphosphonic acid, Acido etidronico
Synthetic
Chelating Agent
Acid
Not Clean
Phosphonic acid, (1-hydroxyethylidene)bis-
Solubility 1.15e+01 g/L
Formula
C2H8O7P2
Mol. Weight
206.03
CAS #
2809-21-4
Form
Liquid
State
Liquid; Dry Powder
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Binds metal ions
Traditional Use
Synthesized in the mid-20th century as a chelating agent. Developed to prevent mineral deposits and oxidation in cosmetic formulations, improving product stability.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
1.5%
0%2%
Reg. Limit
EU regulatory limit: 1.5%. (a) 1.5% (as etidronic acid) (b) 0.2% (as etidronic acid) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 53.
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR