Fumaric Acid

AKA: 110-17-8, Trans-Butenedioic acid, Allomaleic acid, Lichenic acid, Boletic acid, (2E)-but-2-enedioic acid, Tumaric acid, Trans-1, 2-Ethylenedicarboxylic acid, (E)-2-Butenedioic acid
Plant-Derived Synthetic
Acid
Clean
Fumaric acid is a precursor to L-malate in the Krebs tricarboxylic acid cycle. It is formed by the oxidation of succinate by succinate dehydrogenase. Fumarate is converted by fumarase to malate. A fumarate is a salt or ester of the organic compound fumaric acid, a dicarboxylic acid. Fumarate has recently been recognized as an oncometabolite. (A15199). As a food additive, fumaric acid is used to impart a tart taste to processed foods. It is also used as an antifungal agent in boxed foods such as cake mixes and flours, as well as tortillas. Fumaric acid is also added to bread to increase the porosity of the final baked product. It is used to impart a sour taste to sourdough and rye bread. In cake mixes, it is used to maintain a low pH and prevent clumping of the flours used in the mix. In fruit drinks, fumaric acid is used to maintain a low pH which, in turn, helps to stabilize flavor and color. Fumaric acid also prevents the growth of E. coli in beverages when used in combination with s
Solubility less than 1 mg/mL at 72 °F (NTP, 1992)
Formula
C4H4O4
Mol. Weight
116.07
CAS #
110-17-8
Form
Liquid
Functions
Buffering
Stabilizes pH
Fights Bacteria
Traditional Use
Developed as a synthetic food and cosmetic ingredient in the early 20th century. Originally derived from fumitory plant fermentation, it was later synthesized chemically and adopted in skincare for pH buffering and preservative properties.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Non-Comedogenic
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR