Glucoheptonolactone

AKA: D-Glucoheptono-1, 4-lactone, 60046-25-5, (4S, 5S)-3, 4-dihydroxy-5-[(1R, 2R)-1, 2, 3-trihydroxypropyl]oxolan-2-one
Synthetic
Skin Conditioner
Not Clean
D-Gluco-heptonic acid, gamma-lactone, (2csi)-
Formula
C7H12O7
Mol. Weight
208.17
CAS #
60046-25-5
Form
Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A polyhydroxy acid (PHA) developed in the late 20th century as a milder exfoliating ingredient than AHAs and BHAs. Created to offer skin-smoothing benefits with improved tolerability for sensitive skin.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR