Gluconolactone

Gluconolactone 1
Gluconolactone 2
Gluconolactone 3
Gluconolactone 4
Gluconolactone 5
AKA: 90-80-2, Delta-gluconolactone, D-glucono-1, 5-lactone, Gluconic acid lactone, (3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one, D-Gluconic acid lactone, D-Gluconic acid delta-lactone, 1, 5-D-Gluconolactone, Gluconic lactone
Synthetic
Skin Conditioner
Chemical Exfoliant
Synthetic
Clean
Gluconolactone is a naturally occurring polyhydroxy acid (PHA) with metal chelating, moisturizing and antioxidant activity. Gluconolactone can be produced by enzymatic oxidation of D-glucose oxidation. Its ability in free radicals scavenging accounts for its antioxidant property. It is used in cosmetic product and as a coagulant in tofu processing. (NCI05)
Solubility 590000
Formula
C6H10O6
Mol. Weight
178.14
CAS #
90-80-2
State
Dry Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Removes Metal Ions
Conditions Skin
Binds metal ions
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Skin Types
●all-skin-types
Best For
General
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR