Glucosamine HCL

Glucosamine HCL 1
molecular structure · PubChem CID 91431
AKA: D-Glucosamine hydrochloride, (2R, 3R, 4S, 5R)-2-amino-3, 4, 5, 6-tetrahydroxyhexanal hydrochloride, D-Glucose, Hydrochloride, Chitosamine hydrochloride, D-Glucosamine chloride, 2-Amino-2-deoxy-D-glucose hydrochloride, Artrox (TN), D-Glucosamine monohydrochloride
Synthetic
Skin Conditioner
Synthetic
Clean
Origin-Derived (shellfish) or Plant-Derived (corn/fungi)
The Expert Panel for Cosmetic Ingredient Safety concluded that Glucosamine HCl is safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating.
Formula
C6H14ClNO5
Mol. Weight
215.63
CAS #
66-84-2
Form
Liquid
State
White powder; [Alfa Aesar MSDS]
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Reduces Static
Conditions Hair
Reduces flyaways
Softens and detangles hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 832)
Concentration Guide
Leave-on0.0001–0.9%
Rinse-off0.07–5%
0%50%100%
CIR reported use · report published 2026
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR