Glucosamine Sulfate
molecular structure · PubChem
AKA: Glucosamine sulphate, Tiocondramina, Faximin, Dona, Glucosamine Sulfate Salt, D-Glucose, Sulfate (salt), Dolenio, Glusartel
Synthetic
Skin Conditioner
Clean
Glucosamine Sulfate is an amino sugar (2-amino, 2-deoxyglucose) in cell membranes, Glucosamine Sulfate is believed to play a role in cartilage formation and repair. Long-term glucosamine sulfate treatment retards progression of knee osteoarthritis; the mechanism appears to involve glucosamine's role as an essential substrate for glycosaminoglycans and hyaluronic acid, needed for formation of the joint proteoglycan structural matrix. (NCI04)
Formula
C12H28N2O14S
Mol. Weight
456.42
CAS #
29031-19-4
Form
Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A sulfate salt form of glucosamine developed for improved bioavailability; traditionally glucosamine was sourced from marine organisms and used in folk medicine, with modern sulfate formulation optimizing its cosmetic efficacy.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Dermal Absorption 5%
Concentration Guide
Dermal absorption: 5%. Source: CIR Safety Assessment (CIR Seq 832).
Regulatory Agencies
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR