Glucose

AKA: D-Glucopyranose, Glucopyranose, Blood sugar, (3R, 4S, 5S, 6R)-6-(hydroxymethyl)oxane-2, 3, 4, 5-tetrol, Grape sugar, Traubenzucker, Glucosteril, Cartose, Anhydrous glucose
Synthetic
Humectant
Clean
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation. It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated. Glucose is listed on the World Health Organization's List of Essential Medicines, the most
Effective at 48.9%
Solubility Soluble
Formula
C6H12O6
Mol. Weight
180.16
CAS #
50-99-7
Form
Powder
State
Watery odorless colorless liquid. Denser than water and soluble in water. Hence sinks in and mixes with water. (USCG, 1999)
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
A simple sugar, glucose was first isolated in the 19th century. Used in modern cosmetics for humectancy; historically obtained from honey and fruits in traditional preparations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Concentration Guide
3e-05%
97.8%
0%100%
Reported use
CIR reported use: 0.0001-0.18 | 0.00003-97.8
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR