Glucose Glutamate

AKA: WICKENOL 545, L-Glutamic acid, 5-alpha-D-glucopyranosyl ester, L-GLUTAMIC ACID, 5-.ALPHA.-D-GLUCOPYRANOSYL ESTER, GLUCOSE GLUTAMATE [INCI]
Synthetic
Humectant
Skin Conditioner
Hair Care
Not Clean
L-Glutamic acid, 5-.alpha.-d-glucopyranosyl ester
Formula
C11H19NO9
Mol. Weight
309.27
CAS #
59279-63-9
Form
Liquid
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
A modern amino acid-derived compound created for skincare formulations; developed as a humectant and skin-conditioning agent without significant traditional historical use prior to 20th-century cosmetic science.
EWG
3
CIR
Insufficient data
Pregnancy
Yes
CIR Safety Findings
all-shades-safe
Potential Sensitizer
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR