Glyceryl Acetate

AKA: Monoacetin, Glycerol acetate, EASTMAN 9-45, 247-704-6, 2, 3-Dihydroxypropyl acetate, 1-Monoacetin, 106-61-6
Synthetic
Skin Conditioner
Clean
Glyceryl Acetate is the ester of acetic acid and glycerin
Solubility greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
Formula
C5H10O4
Mol. Weight
134.13
CAS #
26446-35-5
Form
Liquid
State
Acetin is a clear colorless to pale yellow viscous liquid with a characteristic odor. (NTP, 1992)
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic ester of glycerin and acetic acid developed in the 20th century. Used as a humectant and preservative in cosmetics without traditional medicinal history.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR