Glyceryl Di-Hydroxystearate

AKA: 122546-20-7, 2, 3-dihydroxypropyl 2, 2-dihydroxyoctadecanoate
Plant-Derived
Emollient
Skin Conditioner
Not Clean
12-Hydroxyoctadecanoic Acid, 2-Hydroxy-1,3-Propanediyl,2-Hydroxy-1,3-Propanediyl 12-Hydroxyoctadecanoate,2'-Hydroxy-1',3'-propylene 12-hydroxystearate,Hydroxystearic Acid, Diester with 1,2,3-Propanetriol,Octadecanoic Acid, 12-Hydroxy-, 2-Hydroxy-1,3-Propanediyl Ester
Formula
C21H42O6
Mol. Weight
390.60
CAS #
122546-20-7
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 441)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR