Glyceryl Dioleate

Glyceryl Dioleate 1
molecular structure · PubChem CID 6505653
AKA: [(2S)-3-hydroxy-2-[(E)-octadec-9-enoyl]oxypropyl] (E)-octadec-9-enoate, Di-oleoylglycerol, ((2S)-3-hydroxy-2-((E)-octadec-9-enoyl)oxypropyl) (E)-octadec-9-enoate, Oleic acid diglyceride, (+--)-1, 2-diolein, 2-dioleoylglycerol, CHEBI:75945, 25637-84-7
Synthetic
Emollient
Skin Conditioner
Clean
OriginDerived from glycerin and oleic acid, both obtainable from plant oils or petroleum sources. Synthesized through esterification reaction between glycerin and oleic acid under controlled heat and catalytic conditions.
Dioleic acid, diester with glycerol
Formula
C39H72O5
Mol. Weight
621.00
CAS #
25637-84-7
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 441)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 441)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 mixed / reactions minimal (CIR 322 and 441)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR