Glyceryl Thioglycolate

AKA: Glyceryl monothioglycolate, 30618-84-9, Glycerol monomercaptoacetate, Acetic acid, Monoester with 1, 2, 3-propanetriol, CHEBI:156545, Mercaptoacetic acid
Synthetic
Not Clean
Mercaptoacetic acid, monoester with propane-1,2,3-triol
Formula
C5H10O4S
Mol. Weight
166.20
CAS #
30618-84-9
Form
Liquid
State
Colorless viscous liquid with a mild sulfurous odor; [Lanza Research MSDS]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Hair Waving Or Straightening
Moisturizing
Strengthens Barrier
Changes hair texture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 mixed / reactions minimal to mild (CIR 128 and 347)
Mixed Skin Irritation Results
34 studies / 18 irritating / 7 mixed / 9 not irritating / reactions slight to severe (CIR 128 and 347)
Mixed Sensitization Results
45 studies / 28 sensitizing / 3 mixed / 14 not sensitizing / plus 8 case reports (CIR 128 and 347)
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR