AKA: Enoxolone, Glycyrrhetic acid, Uralenic acid, 471-53-4, 18-beta-Glycyrrhetinic acid, Enoxolona, 3beta-Hydroxy-11-oxoolean-12-en-30-oic acid, Enoxolonum
WHAT IS IT? Synthetic
Skin Conditioner
Acid
Not Clean
Origin Derived from licorice root (Glycyrrhiza glabra) through selective isolation of the aglycone compound. Produced by enzymatic deglycosylation or chemical hydrolysis of glycyrrhizin to remove sugar moieties.
Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta., 20.beta.)-
IS IT FOR ME? Pregnancy & Breastfeeding Safe
Caution
WHAT’S IT DO? Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
CAN I TRUST THIS? The paper trail
🛡️ Safety-assessed 2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
IS IT CLEAN? CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 349)
Not a Skin Irritant
4 studies / 4 not irritating (CIR 349)
Not a Sensitizer
4 studies / 4 not sensitizing (CIR 349)
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 349)
Regulatory Status
JAPAN ⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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