HC Blue No. 1

AKA: HC Blue 1, 2784-94-3, HC Blue Number 1, NCI-C04159, 2'-((4-(Methylamino)-3-nitrophenyl)imino)diethanol, 1-Methylamino-2-nitro-4-(bis-2-hydroxyethyl)aminobenzene, Ethanol
Synthetic
Clean
1-[(2',3'-Dihydroxypropyl)amino]-2-nitro-4-[methyl-(2'-hydroxyethyl)amino]benzene hydrochloride and other salts
Solubility less than 0.1 mg/mL at 64 °F (NTP, 1992)
Formula
C11H17N3O4
Mol. Weight
255.27
CAS #
173994-75-7, 102767-27-1
Form
Powder
State
Hc blue 1 appears as dark blue microcrystals or dark purple powder. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Dermal Absorption 0.03–0.166%
4 animal and human studies in the CIR safety assessment (CIR 79)
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR