HC Orange No. 1
molecular structure · PubChem
AKA: 54381-08-7, 4-((2-Nitrophenyl)amino)phenol, HC Orange 1, Phenol, 2-Nitro-4'-hydroxydiphenylamine, 4-[(2-nitrophenyl)amino]phenol, COLOREX HCO1
WHAT IS IT?
Synthetic
Not Clean
p-[(o-Nitrophenyl)amino]phenol
Formula
C12H10N2O3
Mol. Weight
230.22
CAS #
54381-08-7
Form
Powder
WHAT DOES IT DO?
Functions
Hair Dyeing
Colors Hair
Traditional Use
A synthetic aromatic amine dye created specifically for hair coloring formulations in the 20th century, designed to provide orange tones in semi-permanent and temporary hair color applications.
IS IT CLEAN?
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Regulatory Status
USA
✔ permitted
EU
✔ permitted
JAPAN
✔ permitted
CANADA
✔ permitted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
IS IT FOR ME?
Skin Types
●
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
CAN I TRUST THIS?
The paper trail
🔬
Peer-reviewed
1 paper →
⚖️
Regulatory
0 listings
🛡️
Safety-assessed
2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR