HDI/PEI-45/SMDI Crosspolymer

HDI/PEI-45/SMDI Crosspolymer molecular structure
molecular structure · PubChem
AKA: Hexamethylene diisocyanate crosspolymer
Synthetic
Not Clean
HDI/PEI-45/SMDI Crosspolymer is the crosslinked polymer formed by the reaction of PEI-45 with saturated methylenediphenyldiisocyanate (SMDI) and hexamethylene diisocyanate (HDI).
Form
Liquid
State
Solid
Functions
Absorbent
Plasticiser
Absorbs excess oil
Adds flexibility
Traditional Use
A synthetic crosspolymer developed in the late 20th century using HDI (hexamethylene diisocyanate) and SMDI (semi-alicyclic methylene diphenyl diisocyanate) chemistry. Designed as a film-forming, binding, and texture-modifying agent in modern skincare and cosmetic products.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR