HDI/Trimethylol Hexyllactone Crosspolymer
molecular structure · PubChem
AKA: Polyurethane crosspolymer, Aliphatic HDI polymer
Synthetic
Clean
OriginSynthesized from hexyllactone, trimethylol compounds, and hexamethylene diisocyanate as starting materials. Produced through a crosspolymerization reaction combining these chemical precursors into a polymeric network structure.
2-Ethyl-2-hydroxymethyl-1,3-propanediol, polymer with tetrahydro-6-methyl-2H-pyran-2-one, reaction products with 1,6-diisocyanatohexane
Form
Liquid
State
Solid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Anticaking
Prevents Clumping
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 704)
Mixed Skin Irritation Results
3 studies / 1 mixed / 2 not irritating / reactions slight (CIR 704)
Mixed Eye Irritation Results
1 study / 1 mixed / reactions slight (CIR 704)
Concentration Guide
Leave-on0.0096–31%
Rinse-off11.7%
0%50%100%
CIR reported use · 2015 survey
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR
murphy