hexadecyl D-glucoside

AKA: 54549-27-8, Hexadecyl D-glucopyranoside, Cetyl glucoside, (3R, 4S, 5S, 6R)-2-hexadecoxy-6-(hydroxymethyl)oxane-3, 4, 5-triol, PAEMERHSTIDLSE-VEIQOZLZSA-N
Synthetic
Cleanser
Not Clean
hexadecyl D-glucoside is a cosmetic ingredient. Also known as 54549-27-8. Assessed as safe by the CIR.
Formula
C22H44O6
Mol. Weight
404.60
CAS #
54549-27-8
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Surfactant
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on3%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2013
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR