murphyHexyl Salicylate
AKA: 6259-76-3, N-HEXYL SALICYLATE, 1-Hexyl salicylate, Benzoic acid, Hexyl ester
Synthetic
Fragrance
Not Clean
OriginSynthesized from salicylic acid and hexanol, belonging to the aromatic ester chemical family. Produced through esterification, combining salicylic acid with hexyl alcohol via acid-catalyzed condensation.
Benzoic Acid, 2-hydroxy-, 2-hexyl ester
Formula
C13H18O3
Mol. Weight
222.28
CAS #
6259-76-3
Form
Liquid
State
Liquid; Dry Powder, Liquid, Other Solid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Antioxidant
Anti-Inflammatory
Moisturizing
Provides scent
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
3
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not Phototoxic
Human test found no phototoxicity in the CIR safety assessment (CIR 766)
Mixed Skin Irritation Results
16 studies / 4 irritating / 2 mixed / 10 not irritating / reactions slight (CIR 766)
Mixed Sensitization Results
8 studies / 3 sensitizing / 5 not sensitizing / plus 1 case report (CIR 766)
Concentration Guide
Leave-on0.013–0.12%
Rinse-off0.032–0.52%
0%50%100%
Reg. limit 0.001%
CIR reported use · 2018 survey
EU/SCCS limit: 0.001% in children. Opinion: SCCS/1668/24
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR