Hexyldodecyl Salicylate

AKA: Salicylic acid, 2-hexyldodecyl ester, 220778-06-3, (+-)-HEXYLDODECYL SALICYLATE, HEXYLDODECYL SALICYLATE [INCI], (+/-)-Hexyldodecyl salicylate
Synthetic
Solvent
Skin Conditioner
Hair Care
Not Clean
OriginSynthesized from salicylic acid and long-chain alcohols (hexyl and dodecyl), belonging to the ester compound family. Produced through esterification reaction between salicylic acid and the respective fatty alcohols under catalytic conditions.
2-Hydroxybenzoic acid, 2-hexyldodecyl ester
Formula
C25H42O3
Mol. Weight
390.60
CAS #
220778-06-3
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Restricted By
Concentration Guide
0%50%100%
Reg. limit 3%
CIR lists it as not reported to be in use.
CIR · report published 2025
EU regulatory limit: 3.0%. (a) 3.0% (b) 2.0%. Not to be used for children under three years of age (11) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 98.
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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