Histidine HCl is a cosmetic ingredient used as hair conditioning, skin conditioning. Also known as L-Histidine hydrochloride. Rated low hazard by EWG. Assessed as safe by the CIR.
Formula
C6H10ClN3O2
Mol. Weight
191.61
CAS #
645-35-2, 5934-29-2
Form
Powder
State
Fine white crystals; [Sigma-Aldrich MSDS]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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