Honokiol

AKA: 35354-74-6, 5'-Diallyl-4, 2'-dihydroxybiphenyl, Purinol, 4-allyl-2-(3-allyl-4-hydroxy-phenyl)phenol, 2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol, FMLT BSASM H
Synthetic
Skin Conditioner
Synthetic
Clean
OriginHonokiol is a neolignan compound derived from magnolia plant species, synthetically manufactured to isolate the active molecule. It is produced through chemical synthesis or semi-synthesis from magnolia bark precursors via extraction and purification methods.
Honokiol is under investigation in clinical trial NCT00966953 (Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.).
Formula
C18H18O2
Mol. Weight
266.30
CAS #
35354-74-6
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Antioxidant Protection
Neutralizes Free Radicals
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR