Human Placental Enzymes

AKA: Placenta extract

Synthetic

Skin Conditioner

Hair Care

Not Clean

Human Placental Enzymes are the enzymes derived from human placentas obtained from normal afterbirth

CAS #

-

Form

Powder

Functions

Hair Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Locks in moisture

Traditional Use

Placental enzymes became a cosmetic ingredient in the early 20th century, particularly in Japanese and European skincare, based on the belief that placental proteins and enzymes could promote cellular turnover and collagen production. Their use in cosmetics remains controversial due to ethical sourcing concerns.

EWG

CIR

Safe as used

Pregnancy

Caution

CIR Safety Findings

Not a Sensitizer

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

EU✔ permitted

JAPAN✔ permitted

CANADA✔ permitted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

Uneven Texture

Pregnancy & Breastfeeding Safe

Caution

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory0 listings

🛡️Safety-assessed2 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR