Hydrolyzed Actin

AKA: Actin Hydrolysate
Synthetic
Skin Conditioner
Hair Care
Clean
OriginDerived from actin protein, typically sourced from animal muscle tissue or produced through microbial fermentation. Hydrolyzed through enzymatic or chemical breakdown to reduce protein chain length for cosmetic application.
Actins, hydrolyzates. Substance obtained by hydrolysis of actin, composed primarily of proteins, peptides and amino acids
CAS #
222400-31-9
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on1.6%
Rinse-off0.00075%
0%50%100%
CIR reported use · 2016 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR