Hydrolyzed Actin
molecular structure · PubChem
AKA: Actin Hydrolysate
Synthetic
Skin Conditioner
Hair Care
Clean
Actins, hydrolyzates. Substance obtained by hydrolysis of actin, composed primarily of proteins, peptides and amino acids
Effective at 8.25%
CAS #
222400-31-9
Form
Powder
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Actin is a muscle protein; hydrolyzed actin is a modern ingredient developed for cosmetic formulations. Its use in skincare is based on contemporary research into protein hydrolysates as humectants and conditioning agents rather than traditional medicine.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
4e-06%
16.5%
0%100%
Reported use
CIR reported use: 0.000004-6 | 0.00003-16.5
Regulatory Agencies
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR