Hydrolyzed Fibronectin
molecular structure · PubChem
AKA: Fibronectin Hydrolysate, Soluble Fibronectin
Synthetic
Skin Conditioner
Hair Care
Clean
Protein hydrolyzates, fibronectin. Substance obtained by acidic, alkaline, or enzymatic hydrolysis of fibronectin composed primarily of amino acids, peptides, and proteins. It may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous organic substances of biological origin
Effective at 8.25%
CAS #
100085-35-6
Form
Powder
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Fibronectin is a human protein identified in the 1970s; the hydrolyzed form was later developed for cosmetics as a modern ingredient to support skin matrix and conditioning properties.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
4e-06%
16.5%
0%100%
Reported use
CIR reported use: 0.000004-6 | 0.00003-16.5
Regulatory Agencies
Skin Types
●all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR